List of cities in Puerto Rico (US) by population. There are 137 cities in Puerto Rico (US), of which San Juan is the largest in terms of population - 381 953. The total number of people in Puerto Rico (US) is 3 411 335 for 2026.
| # | Name, city | Population |
|---|---|---|
| 1 | San Juan | 381 953 |
| 2 | Bayamon | 208 165 |
| 3 | Carolina | 186 091 |
| 4 | Ponce | 155 059 |
| 5 | Caguas | 142 096 |
| 6 | Mayagüez | 104 571 |
| 7 | Aguadilla | 66 323 |
| 8 | Humacao | 54 915 |
| 9 | Cayey | 47 415 |
| 10 | Guayama | 45 432 |
| 11 | Aguada | 42 042 |
| 12 | Fajardo | 40 766 |
| 13 | Lares | 33 033 |
| 14 | Salinas | 31 123 |
| 15 | Luquillo | 19 856 |
| 16 | Ceiba | 18 369 |